CBD for Crohn’s Disease and Ulcerative Colitis

The use of CBD against the symptoms of Crohn’s disease and ulcerative colitis has become widespread. Does it really work? Here we’ll tell you….CONTINUE READING

In recent years, the consumption of cannabidiol (CBD) has aroused interest among those suffering from Crohn’s disease and ulcerative colitis . The reason? Some studies suggest that it has positive effects on symptom control and an increased sense of well-being . Stay with us as we see whether CBD for Crohn’s disease is effective or not.

Both disorders are grouped into the so-called irritable bowel syndrome

(IBS), which is characterized by the presence of cramps, diarrhea or constipation. They are inflammatory in nature and are associated with an altered immune system response. However, other factors are involved in each condition.

While Crohn’s disease penetrates the intestinal wall and affects more than one section, ulcerative colitis only involves the inner lining of the intestine. Whatever the case, quality of life is diminished, especially when symptoms tend to become more acute. Does CBD for Crohn’s disease work?
Cannabidiol (CBD) is one of the main compounds in the Cannabis sativa plant . It’s also the substance to which much of the medicinal effects of this species are attributed.

As explained in an article shared in the National Center for Biotechnology Information , it differs from THC in that it does not have psychoactive effects. On the contrary, there is evidence of its anti-inflammatory, analgesic, anxiolytic, antiemetic, and neuroprotective activity.
Studies

have also determined that this cannabinoid has positive effects in patients with Crohn’s disease and ulcerative colitis. While not a substitute for medical treatment, it appears promising as an adjunct for symptom control .

A review reported in Phytotherapy Research

suggests that CBD is a promising treatment for inflammatory bowel diseases. This is apparently due to its ability to interact with the body’s endocannabinoid system (ECS) , which, in turn, influences the normal functioning of the gastrointestinal system.

However, as another review in Expert Review of Gastroenterology & Hepatology

points out, research on cannabis and its potential against Crohn’s disease and ulcerative colitis is still in the early stages.

According to this paper, so far there are only three small placebo-controlled studies on the use of CBD for Crohn’s disease in humans

. Of these, only two showed clinical improvement, but none showed relevant changes in inflammation.

Even so, it’s a topic that remains under study. Experts emphasize

that no firm conclusions can be drawn about its safety and efficacy in the management of these disorders.

They point out that more comprehensive studies are needed, which would also make it possible to determine the appropriate doses and forms of administration.

No optimal dose has been established for the consumption of CBD for Crohn’s disease and ulcerative colitis. That poses a problem, as it prevents us from determining the doses that may be safe for these patients . At the doses tested, results have been mixed.

In a clinical trial shared in Inflammatory Bowel Diseases ,some participants didn’t tolerate well doses of 50 mg twice daily of a CBD extract. Furthermore, in another study , 90% of patients reported side effects and many opted to discontinue treatment.

Of these, the main reaction reported was dizziness. However, other unwanted effects have been described, such as diarrhea, fatigue, and changes in appetite and weight.

And although the authors of several studies add that CBD is safe in most cases, the Food and Drug Administration (FDA)

hasn’t yet approved its use for this pathology. In fact, it warns that it can trigger the following problems:

Despite the experts’ warning about the lack of studies on CBD for Crohn’s disease and ulcerative colitis, many patients are attracted to this type of treatment. Thus, anecdotal evidence of its effects has grown considerably. Because of this, many people consult online stores and herbalists for these supplements on a daily basis.

They are often available in the form of pills and capsules, oils and tinctures, lotions, and creams. It’s paramount to consult the manufacturer’s recommendations for the proper use of each. But, apart from choosing one option or another, we must be aware that medical treatments must be continued.

This includes the use of medication, lifestyle changes, and any other therapy suggested by the specialist. If possible, you should tell your doctor about your intention to try CBD. It shouldn’t be overlooked that there may also be interactions with other prescription drugs or supplements….CONTINUE READING